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Medicinal Chemistry (8343.4)

Level: Level 3 - Undergraduate Advanced Unit
Credit Points: 3
HECS Bands: 2, 4
Faculty: Faculty of Science and Technology
Discipline: Academic Program Area - Science

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    Unit Outlines

    To view your Unit Outline, click View to log in to MyUC and access this information, or visit your unit's online teaching site.

    • Semester 1, 2018, ON-CAMPUS, BRUCE (182249) - View
    • Semester 1, 2017, ON-CAMPUS, BRUCE (165732) - View
    • Semester 1, 2016, ON-CAMPUS, BRUCE (154041) - View
    • Semester 1, 2015, ON-CAMPUS, BRUCE (146147) - View

    If a link to your Unit Outline is not displayed, please check back later. Unit Outlines are generally published by Week One of the relevant teaching period.

    Syllabus

    This unit aims to develop the ability of students to correlate chemical structure with the physicochemical properties and biological activity of drug molecules. These principles will be applied to the design, production and optimisation of both historical and new drug entities. This unit will integrate the concepts of structure ? activity relationships and the chemistry behind drug activity with the processes and techniques used in the chemical synthesis of pharmacological agents. Synthesis and retrosynthesis of antifungal drugs, antibacterial drugs, central nervous system agents, antibiotics, illicit drugs, drugs for ADHD, Parkinson, mental depression diseases and their mode of actions will be discussed. This unit is co-taught with Medicinal Chemistry G.

    Learning Outcomes

    On completion of this unit, students will be able to:

    1. Recognise chemical structures of common medicinal agents and understand the reactivity of common functional groups;

    2. Describe the mode of action of biologically active compounds;

    3. Be familiar with the methods used to develop new chemical entities with pharmacologic activity as well as optimise existing drugs;

    4. Apply their knowledge to the chemical basis for synthesis of medicinal products and relate their chemical knowledge to the issues confronting pharmaceutical scientists;

    5. Use the organic reactions that they have previously encountered to design syntheses of biologically active compounds;

    6. Use their knowledge about functional groups and properties to predict the physical and chemical properties of the biologically active compounds; and

    7. Develop their generic skills and attributes in communication and lifelong learning.

    Assessment Items

    Contact Hours

    2 hour tutorial and 2 hours laboratory class/week.

    Prerequisites

    Chemistry 1b, 1517, or equivalent.

    Corequisites

    None.

    Assumed Knowledge

    Basics in chemistry.

    Equivalent Units

    None.



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