Qualifications & Experience

• 1994 - Bachelor of Biotechnology (Honours), Flinders University of South Australia
• 2000 - Graduate Diploma in Sciences Communication, Central Queensland University
• 2000 - PhD (Health Sciences), Department of Biotechnology, Flinders University of South Australia 
• 1999-2000: Research Assistant, Departments of General Practice and Medicine, Flinders University
• 2000-2003: Postdoctoral Fellow, Department of Molecular Pharmacology & Experimental Therapeutics, Mayo Clinic USA
• 2006 Certificate in Clinical Research, Mayo Clinic and Graduate School
• 2003-2007: Postdoctoral Fellow, Molecular Genetics Group, Division of Molecular Biosciences, John Curtin School of Medical Research, Australian National University

Research Interests

• Pharmacogenetics of Phase II metabolic enzymes and adverse drug reactions
• Functional characterisation of novel glutathione transferases (GSTs)
• Understanding the role of GSTs in mitochondrial function
• Regulation of metabolic enzymes and how this contributes to disease• 

Publications

Shield AJ, Murray TP, and Board PG (2006) Functional characterisation of ganglioside-induced differentiation-associated protein 1 as a glutathione transferase. Biochem Biophys Res Commun. 347(4):859-66.

Shield AJ, Thomae BA, Eckloff BW, Weiben ED, Weinshilboum RM. (2004) Human catechol O-methyltransferase (COMT): Gene resequencing and functional characterisation of polymorphisms. Molecular Psychiatry 9:151-160.

Shield AJ, Webb GC and Sanderson BJS (2004) Recombinant models for assessing the role of GSTM1 in styrene-7,8-oxide mutagenicity. Toxicology 195: 61-68.

Shield AJ and Sanderson BJS (2001) Role of Glutathione-S-Transferase Mu (GSTM1) in styrene-7,8-oxide toxicity and mutagenicity. Environmental and Molecular Mutagenesis 37: 285-289.
Sanderson BJS and Shield AJ (1996) Mutagenic damage to mammalian cells by therapeutic alkylating agents. Mutation Research 355: 41-57.