Viral Immunology, Emerging Infections

Research Interests

• Influenza virus pathogenesis
• Interferon-induced proteins with antiviral activities
• Mc proteins
• ADAR proteins

Representative Publications

M. Frese and E. Dazert (2008). Interferon-induced effector proteins and hepatitis C virus replication. In: E. Jirillo (eds), Hepatitis C virus Disease: Immunobiology and Clinical Application. Springer, New York, USA.

Pietschmann, T., Frese, M. and Bartenschlager, R. (2004) Novel insights into hepatitis C virus replication and persistance. Adv. Virus Res. 63: 71-180.

Krnke, M., Kittler, R., Buchholz, F., Windisch, M.P., Pietschmann, T., Bartenschlager, R. and Frese, M. (2004) Alternative approaches for efficient inhibition of hepatitis C virus RNA replication. J. Virol. 78: 3436-3446.

Frese, M., Schwrzle, V., Barth, K., Krieger, N., Lohmann, V., Mihm, S., Haller, O. and Bartenschlager, R. (2002) Interferon-gamma inhibits subgenomic and genomic hepatitis C virus replicons. Hepatology 35:694-703 (cover story).

Frese, M., Pietschmann, T., Moradpour, D., Haller, O. and Bartenschlager, R. (2001) Interferon-alpha inhibits hepatitis C virus subgenomic RNA replication by an MxA-independent pathway. J. Gen. Virol. 82: 723-733.

Frese, M., Kochs, G., Feldmann, H., Hertkorn, C. and Haller, O. (1996) Inhibition of bunyaviruses, phleboviruses and hantaviruses by human MxA protein. J. Virol. 70: 919-923.

Current Students

PhD

Eva Dazert, University of Heidelberg (Germany) (Characterization of the interferon-induced inhibition of hepatitis C virus replication)

Ali Zaid, Cytokine modulation by RNA viruses

Abbreviated CV

Employment History

2008 -           Senior Lecturer, School of Health, University of Canberra

2006 - 2007 Lecturer, School of Health Sciences, University of Canberra

2002 - 2006 Research Fellow, Department of Molecular Virology, University of Heidelberg (Germany)

1998 - 2002 Research Fellow, Department of Virology, University of Freiburg (Germany)

1997 - 1998 Research Fellow, Devision of Plant Biology, The Scripps Research Institute, La Jolla, California (USA)

1996 - 1997 Research Fellow, Department of Virology, University of Freiburg (Germany)

1992 - 1996 Research Officer, Department of Virology, University of Freiburg (Germany)

Academic Degrees

1996 PhD, University of Freiburg, Germany

1992 Diplom, University of Osnabrck, Germany

Prizes, Scholarships, Fellowships and Awards

2007 Fellow of the Australian Society for Microbiology (FASM)

2007 Poster prize (as a senior author) of the Symposium of the German Hepatitis Network, Hannover (Germany)

2004 Poster prize (as a senior author) of the International Symposium on Hepatitis C and Related Viruses, Heidelberg (Germany)

1997 - 1998 Postdoctoral fellowship from the Deutsche Forschungsgemeinschaft (DFG) which I used to do research at The Scripps Research Institute, La Jolla (USA)

1993 Elected student participant of the Nobel Laureate Conference, Lindau (Germany)

1992 - 1997 Travelling awards from the Scientific Society of Freiburg (Germany) and the Hoffman-La Roche Foundation, Basel (Switzerland)

1990 Student award for excellent performance from the Lower Saxony Ministry of Science and Art (Germany)